Scoring 27 first-half points, including a pair of interception returns for touchdowns, the Tribe (2-1) romped to a 34-6 victory over the host Leopards (0-2) Saturday night.
It was sweet revenge for a W&M team that fell 17-14 at home to Lafayette in 2012 en route to a 2-9 season.
Mikal Abdul-Saboor rushed for 103 yards and two touchdowns on 14 carries for the Tribe, which outrushed Lafayette 245 yards to 73.
Michael Graham added 69 yards on six rushes, as well as completing 9-of-17 for 146 yards. Sean Ballard made six receptions for 105 yards.
The Leopards lost two fumbles in Tribe territory. Lafayette’s Zach Zweizig was 31-of-47 for 239 yards, including 18-of-22 in the first half, but two passes cost him dearly.
Marcus Harvey’s 29-yard interception return with 5:33 left in the first quarter made it 13-0, and Airek Green’s 25-yard pick-six boosted the margin to 20-0. Kendell Anderson rushed for a Tribe TD.
W&M (2-1), which dominated Hampton last week after playing well in a loss at West Virginia in its opener, now heads into its Colonial Athletic Association schedule.
Ross Scheuerman added 53 yards rushing and Ryan Gralish kicked a pair of field goals for Lafayette, including one that made it 27-6 with 1:33 left in the third quarter.
However, Abdul-Saboor extinguished any of the Leopards' potential momentum with a 13-yard TD early in the fourth.