Junior guard Marcus Thornton scored 25 points, helping W&M build a big lead and hold on for an 82-70 victory at Matthews Arena.
Thornton was one of four players who scored in double figures for William and Mary (15-8, 7-3 Colonial Athletic Association), which has won five of its last six games and is in third place in the nine-team CAA.
Senior forward Tim Rusthoven and freshman swingman Omar Prewitt scored 13 points apiece, while senior guard Brandon Britt added 12 for the Tribe.
Junior guard Demetrius Pollard -- a Cape Henry Collegiate product -- scored 13 points for Northeastern (8-17, 5-6), which has lost three of its last four. Freshman guard T.J. Williams had 12 points and junior forward Scott Eatherton added 11.
W&M started the game with an 8-0 run and took a 15-4 lead on a layup by Thornton with 14 minutes remaining in the opening period. The Tribe extended its lead to 23-8 on a 3-pointer by senior guard Julian Boatner with 10:59 to go.
The Tribe continued to build on its advantage, mounting a 17-2 run to take a 40-11 lead on two free throws by Britt with 4:15 remaining. The Tribe shot a sizzling 60.7 percent in the first half and made 5 of 8 from 3-point range, while the Huskies shot 23.1 percent and missed all 10 of their attempts from beyond the arc.
William and Mary led 45-18 at the break and continued to dominate early in the second half. The Tribe took a 60-27 lead on a dunk by senior forward Kyle Gaillard with 13:13 to play, but then Northeastern began to battle back.
The Huskies staged 6-0, 8-0 and 14-0 runs to cut William and Mary's lead to 67-57 with 2:30 remaining, but they couldn't get any closer.